Story thread · 2 reports / 2 sources
Temporal uncoupling of radial glia lineage progression in cortical organoids
nature.com · 22h · first report
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10916-7 RGP lineage tracing in stem-cell-derived organoids shows highly plastic proliferation and reduced clonal neuronal diversity, indicating that missing non-cell-autonomous niche cues are essential for faithful temporal control of cortical lineage progression.
The coverage
- Cortical Organoids Reveal Radial Glial Progenitor Lineage Dynamics
genengnews.com · 2h
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