Story thread · 2 reports / 2 sources

3D DNA mapping in rare immune cells reveals new genes linked with autoimmune disease risk

phys.org · 7dShare

Our DNA is often pictured as a simple spiral, like a piece of rope held taut. But inside cells, it folds into a complex three-dimensional structure, with 2 meters (6.6 feet) of DNA scrunched like a headphone wire in a pocket. This bundled architecture plays a crucial role in how genes are switched on and off. Understanding these interactions is key to interpreting genetic studies of disease and can help develop targeted treatments.

First report: Genome Mapping Reveals Autoimmune Disease Risk Genes in Innate Lymphoid Cells — genengnews.com, 7d