Story thread · 3 reports / 2 sources

Keeping stem cells in check: A new mechanism by which cell junction proteins regulate tissue homeostasis

phys.org · 12dShare

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.

First report: Intestinal stem cells count self-renewal divisions to switch multipotency — nature.com, 13d